Magnetic Gold Composite Nanoshells for Nanomedicine Devices

Gold Nanoshells in Biomedical Applications

Gold nanocages as multifunctional materials for nanomedicine

Featured by tunable localized surface plasmon resonance peaks in the near-infrared region and hollow interiors, Au nanocages represent a novel class of multifunctional nanomaterials that have gained considerable attention in recent years. This short review summarizes our recent work on the capabilities of Au nanocages in nanomedicine. We start with a brief description of the synthesis of Au nan...

Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer.

Image-guided thermal ablation of tumors is becoming a more widely accepted minimally invasive alternative to surgery for patients who are not good surgical candidates, such as patients with advanced head and neck cancer. In this study, multifunctional superparamagnetic iron oxide coated with gold nanoshell (SPIO@Au NS) that have both optical and magnetic properties was conjugated with the targe...

Magnetically mediated vortexlike assembly of gold nanoshells.

Gold nanoshells currently attract increasing research interests due to the important role in many subjects. For practical applications, random arrangement of the nanoparticles is often unfavored so that the assembly of gold nanoshells is becoming a central issue. We here proposed to utilize time-variant magnetic field to direct the assembly of gold nanoshells. It was discovered that the alterna...

A whole blood immunoassay using gold nanoshells.

A rapid immunoassay capable of detecting analyte within complex biological media without any sample preparation is described. This was accomplished using gold nanoshells, layered dielectric-metal nanoparticles whose optical resonance is a function of the relative size of its constituent layers. Aggregation of antibody/nanoshell conjugates with extinction spectra in the near-infrared was monitor...